{"id":5336,"date":"2023-09-16T06:50:30","date_gmt":"2023-09-16T04:50:30","guid":{"rendered":"https:\/\/parlonstechs.com\/all\/?p=5336"},"modified":"2023-09-16T06:53:11","modified_gmt":"2023-09-16T04:53:11","slug":"des-resultats-positifs-pour-un-vaccin-contre-le-cancer-du-poumon","status":"publish","type":"post","link":"https:\/\/parlonstechs.com\/all\/2023\/09\/16\/des-resultats-positifs-pour-un-vaccin-contre-le-cancer-du-poumon\/","title":{"rendered":"Des R\u00e9sultats positifs pour un vaccin contre le cancer du poumon"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"538\" src=\"https:\/\/parlonstechs.com\/all\/wp-content\/uploads\/2023\/09\/image-53.png\" alt=\"\" class=\"wp-image-5337\" srcset=\"https:\/\/parlonstechs.com\/all\/wp-content\/uploads\/2023\/09\/image-53.png 1024w, https:\/\/parlonstechs.com\/all\/wp-content\/uploads\/2023\/09\/image-53-300x158.png 300w, https:\/\/parlonstechs.com\/all\/wp-content\/uploads\/2023\/09\/image-53-768x404.png 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-medium-font-size\"><strong>La soci\u00e9t\u00e9 fran\u00e7aise de biotechnologie OSE Immunotherapeutics a pr\u00e9sent\u00e9 lundi des r\u00e9sultats positifs de son vaccin th\u00e9rapeutique Tedopi chez des patients atteints de cancer avanc\u00e9 du poumon qui d\u00e9montrent une diminution du risque de d\u00e9c\u00e8s par rapport \u00e0 la chimioth\u00e9rapie.<\/strong><\/p>\n\n\n\n<p><em>Un an apr\u00e8s le d\u00e9but du traitement, 44,1% de ces patients \u00e9taient toujours en vie dans le groupe recevant le vaccin contre seulement 27,5% dans le groupe chimioth\u00e9rapie<\/em>, selon les r\u00e9sultats d&rsquo;un essai clinique de phase 3 (\u00e9tape qui pr\u00e9c\u00e8de la commercialisation) qui ont \u00e9t\u00e9 publi\u00e9s lundi dans la revue Annals of Oncology.<\/p>\n\n\n\n<p><em>L\u2019\u00e9tude montre \u00e9galement que le vaccin \u00e0 la place de la chimioth\u00e9rapie permet de maintenir une meilleure qualit\u00e9 de vie des patients et moins d&rsquo;effets secondaires,<\/em>&nbsp;indique le professeur Benjamin Besse, directeur de la recherche clinique \u00e0 l&rsquo;Institut Gustave-Roussy et investigateur principal de l\u2019essai baptis\u00e9 Atalante-1.<\/p>\n\n\n\n<p>Ces r\u00e9sultats&nbsp;<em>permettent d&rsquo;envisager un nouvel espoir pour ces patients<\/em>, a d\u00e9clar\u00e9 le directeur g\u00e9n\u00e9ral d&rsquo;Ose Immunotherapeutics, Nicolas Poirier, au cours d&rsquo;une conf\u00e9rence de presse virtuelle, soulignant que plus de un millier d&rsquo;injections avaient \u00e9t\u00e9 r\u00e9alis\u00e9es au cours des diff\u00e9rentes \u00e9tudes cliniques.<\/p>\n\n\n\n<p>Les vaccins th\u00e9rapeutiques anticanc\u00e9reux visent \u00e0 \u00e9duquer le syst\u00e8me immunitaire pour reconna\u00eetre et d\u00e9truire sp\u00e9cifiquement les cellules tumorales.&nbsp;Le vaccin Tedopi est efficace chez les patients disposant du g\u00e8ne HLA-A2, pr\u00e9sent dans la moiti\u00e9 de la population, souligne Ose Immunotherapeutics.<\/p>\n\n\n\n<p>Les patients entrant dans l\u2019essai randomis\u00e9 ont \u00e9t\u00e9 pr\u00e9alablement trait\u00e9s par une chimioth\u00e9rapie et une immunoth\u00e9rapie.<\/p>\n\n\n\n<p><em>L&rsquo;\u00e9tude n&rsquo;est pas all\u00e9e au terme de son recrutement \u00e0 cause de l&rsquo;arriv\u00e9e du Covid-19 et n&rsquo;a donc pas la puissance voulue mais elle permet de comprendre quelle est la population qui a tir\u00e9 un b\u00e9n\u00e9fice r\u00e9el<\/em>&nbsp;du vaccin, \u00e0 savoir les patients qui ont r\u00e9pondu dans un premier temps \u00e0 l&rsquo;immunoth\u00e9rapie avant de rechuter, a indiqu\u00e9 le Pr Besse.<\/p>\n\n\n\n<p>Un total de 219 patients ont particip\u00e9 \u00e0 l&rsquo;\u00e9tude dans neuf pays europ\u00e9ens et aux Etats-Unis (139 patients sous Tedopi et 80 sous chimioth\u00e9rapie).&nbsp;Le vaccin a \u00e9t\u00e9 administr\u00e9 initialement toutes les trois semaines, puis toutes les huit semaines pendant un an, puis toutes les 12 semaines.<\/p>\n\n\n\n<p>Mais Tedopi doit encore \u00eatre test\u00e9 lors d\u2019un nouvel essai au d\u00e9but de l\u2019ann\u00e9e prochaine avant la demande d\u2019autorisation de mise sur le march\u00e9 en 2027.<\/p>\n\n\n\n<p>avec africanews<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La soci\u00e9t\u00e9 fran\u00e7aise de biotechnologie OSE Immunotherapeutics a pr\u00e9sent\u00e9 lundi des r\u00e9sultats positifs de son vaccin th\u00e9rapeutique Tedopi chez des patients atteints de cancer avanc\u00e9 du poumon qui d\u00e9montrent une [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":5339,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,206,229,18],"tags":[],"class_list":["post-5336","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualite","category-medecine","category-sante","category-sciences"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Des R\u00e9sultats positifs pour un vaccin contre le cancer du poumon - Parlons Techs - Store<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/parlonstechs.com\/all\/2023\/09\/16\/des-resultats-positifs-pour-un-vaccin-contre-le-cancer-du-poumon\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta 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